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References National Center for Complementary and Integrative Health

The SUSTAIN cardiovascular outcome trial programme demonstrating significant reduction in major adverse cardiovascular events in type 2 diabetes patients, and the SELECT trial demonstrating cardiovascular event reduction in obese patients without diabetes, have further established Semaglutide as a cardioprotective agent with GLP-1R-mediated cardiovascular biology extending beyond glycaemic and weight management

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Constipation , diarrhea, and bloating round out the gastrointestinal effects that most users experience to some degree