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Seeds Office Hours Episode 091 William Seeds, MD Jun 3, 2026 GLP-1 and the GutMusculoskeletal Axis: A Clinical Summary The Overlooked Connection: Dysbiosis and Degenerative Disease Degenerative musculoskeletal diseases, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc degeneration (IVDD), affect well over a billion people globally and share three core pathological features: chronic inflammation, oxidative stress, and dysregulated cell death

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Each compound was also incubated in the absence of pancreatin (8.3 L of the oligomer stock solution was diluted with 190 L of TRIS 10 mM pH 7.5)

GGT below 20 U/L is ideal

Don't let it sit on the lab bench