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doi: 10.1056/NEJMoa2416394

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Ethics declarations Competing interests D.H.R has received personal remuneration from services as a scientific advisor to Abbvie, Altimmune, Amgen, AstraZeneca, Boehringer Ingelheim, Biohaven, Calibrate, Carmot/Roche, CINRx, Currax, Epitomee, Fractyl, Gila, Lilly, Nestle, Novo Nordisk, Pfizer, Regeneron, Scientific Intake, Source Bio, Structure Therapeutics, Wondr Health, and Zealand, She serves on Speakers Bureau for Novo Nordisk and Lilly